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KMID : 1161920140110020174
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Journal of Medicine and Life Science
2014 Volume.11 No. 2 p.174 ~ p.178
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Relation between visceral & subcutaneous abdominal fat area and insulin sensitivity indices
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Kim Ji-Hyon
Moon Ji-Hyeon
Kim Hyeon-Ju
Kong Mi-Hee
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Abstract
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Obesity is associated with complications such as hyperlipidemia, hyperinsulinemia, hypertension and cardiovascular diseases. We studied the relation of visceral & subcutaneous abdominal fat area and insulin sensitivity indices in nondiabetics Korean adults. This is a cross-sectional study by 204 patients who visited a Health Promotion Center of one hospital. We analyzed the association of anthropometry(waist circumference, BMI), visceral & subcutaneous fat by abdominal fat CT, insulin sensitivity or resistance indices(HOMA-IR, QUICKI, 1/insulin, Glucose/insulin), and plasma concentrations of lipid profiles. We found that in men, VFA and VSR have a negative correlation with Insulin sensitivity indices(QUICKI, 1/fasting insulin, G/I ratio) and a positive correlation with cholesterol and HOMA-IR. In women, we found that VFA and VSR have a negative correlation with HDL-cholesterol and QUICKI and positive correlation with triglyceride and HOMA-IR. After adjusted for age, BMI and waist circumference, we found that only in men, VFA and VSR have a negative correlation with Insulin sensitivity index(QUICKI, 1/fasting insulin, G/I ratio). As shown above, in men, Visceral fat & visceral fat/subcutaneous fat ratio are related strongly to Insulin resistance and sensitiviyt index.
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KEYWORD
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Visceral fat, Subcutaneous fat, Metabolic Syndrome, Insulin Resistance
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